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Association mapping of morphological traits in wild and captive zebra finches : reliable within but not between populations [Molecular Ecology]

Keywords : quantitative trait locus, association study, morphology, genotype-phenotype maps, linkage mapping, standing genetic variation

par Frédéric Magné - publié le , mis à jour le

Identifying causal genetic variants underlying heritable phenotypic variation is a longstanding goal in evolutionary genetics. We previously identified several quantitative trait loci (QTL) for five morphological traits in a captive population of zebra finches (Taeniopygia guttata) by whole-genome linkage mapping. We here follow up on these studies with the aim to narrow down on the quantitative trait variants (QTN) in one wild and three captive populations. First, we performed an association study using 672 single nucleotide polymorphisms (SNPs) within candidate genes located in the previously identified QTL regions in a sample of 939 wild-caught zebra finches. Then, we validated the most promising SNP-phenotype associations (n = 25 SNPs) in 5,228 birds from four populations.(...)

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